陈潇，博士，副教授，硕士生导师，2011年本科毕业于南京大学生命科学学院，2017年获得南京大学药学博士学位，2020年入职必赢bwin网页版官网。主要研究方向为抗肿瘤和阿尔兹海默症药物作用机制研究和治疗靶点发现。任职以来，先后主持国家自然科学基金1项、江苏省自然科学基金1项、校级课题1项，参与国家及省部级课题多项。以第一作者在Signal Transduction and Targeted Therapy, Theranostics等国际期刊发表SCI论文8篇，担任Phytomedicine, Frontiers in Pharmacology等期刊审稿人。作为导师组成员，先后获得江苏省本科优秀毕业论文团队和必赢官方网站首页本科优秀毕业论文团队。
联系方式：xchen@cpu.edu.cn
发表论文：
1. Chen X, Wang Y, Tian J, Shao Y, Zhu B, Wang J, Hua Z. Quantitative Chemical Proteomics Reveals Resveratrol Inhibition of A549 Cell Migration Through Binding Multiple Targets to Regulate Cytoskeletal Remodeling and Suppress EMT. Frontiers in pharmacology. 2021 Mar 26;12:368.
2. Wang Y, Huang J, Wang Z, Wang X, Liu H, Li X, Qiao H, Wang L, Chen J, Chen X*, Li J*. Extra Virgin Olive Oil-Based Phospholipid Complex/self-microemulsion Enhances Oral Absorption of Salvianolic Acid B through Inhibition of Catechol-O-methyltransferase-mediated Metabolism. International Journal of Pharmaceutics. 2021 Dec 2:121330.
3. Chen X, Wang Y, Ma N, Tian J, Shao Y, Zhu B, Wong YK, Liang Z, Zou C, Wang J. Target identification of natural medicine with chemical proteomics approach: probe synthesis, target fishing and protein identification. Signal Transduction and Targeted Therapy. 2020 May 21;5(1):1-3.
4. Chen X, Li W, Xu C, Wang J, Zhu B, Huang Q, Chen D, Sheng J, Zou Y, Lee YM, Tan R. Comparative profiling of analog targets: a case study on resveratrol for mouse melanoma metastasis suppression. Theranostics. 2018;8(13):3504.
5. Chen X, Wang J, Fu Z, Zhu B, Wang J, Guan S, Hua Z. Curcumin activates DNA repair pathway in bone marrow to improve carboplatin-induced myelosuppression. Scientific reports. 2017 Dec 18;7(1):1-1.
6. Chen X, Zhang J, Yuan L, Lay Y, Wong YK, Lim TK, Ong CS, Lin Q, Wang J, Hua Z. Andrographolide suppresses MV4-11 cell proliferation through the inhibition of FLT3 signaling, fatty acid synthesis and cellular iron uptake. Molecules. 2017 Sep;22(9):1444.
7. Chen X, Wong YK, Lim TK, Lim WH, Lin Q, Wang J, Hua Z. Artesunate activates the intrinsic apoptosis of HCT116 cells through the suppression of fatty acid synthesis and the NF-κB pathway. Molecules. 2017 Aug;22(8):1272.
8. Chen X, Wong YK, Wang J, Zhang J, Lee YM, Shen HM, Lin Q, Hua ZC. Target identification with quantitative activity based protein profiling (ABPP). Proteomics. 2017 Feb;17(3-4):1600212.
9. Fu Z, Chen X, Guan S, Yan Y, Lin H, Hua ZC. Curcumin inhibits angiogenesis and improves defective hematopoiesis induced by tumor-derived VEGF in tumor model through modulating VEGF-VEGFR2 signaling pathway. Oncotarget. 2015 Aug 14;6(23):19469.
